I came across this today:

https://github.com/facebook/FBSimulatorControl5

which was also mentioned at last Selenium conference.

Will this type of functionality be implemented in Appium at some point? I haven't really used Appium so far but last I recall it can only handle one iOS simulator/app at a time if I'm not mistaken.

Good to know wreed, should have checked before sort of duplicate posting.

I asked same on ios-driver forum. The developer responded he tried to do similar before but not succeeded, and welcomed any help in the area.

So still new territory I guess.